Definition of "murrain"

For heauen it selfe shall their successe enuy, / And them with plagues and murrins pestilent / Consume, till all their warlike puissaunce be spent.

1590, Edmund Spenser, “Book III, Canto III”, in The Faerie Queene. […], London: […] [John Wolfe] for William Ponsonbie

[Raph.] By this old shooe I shall find out my wife. Firke. Ha, ha olde shooe that wert new, how a murren came this ague fit of foolishnesse upon thee!

1599 (first performance; published 1600), Thomas Dekker, “The Shomakers Holiday. Or The Gentle Craft. […]”, in The Dramatic Works of Thomas Dekker […], volume I, London: John Pearson […], published 1873, Act IV, scene ii, page 54

Nurse. Let him take what he gets, an' a murrain to him! he had no business to bring her here to torment us all, after the dear lady we have lost.

1802, Joanna Baillie, A Series of Plays on the Passions of the Mind, III, The Second Marriage: Act 2, Scene 5

A murrain on thy voice! it is enough to fray every hawk from the perch.

1825 June 22, [Walter Scott], chapter VII, in Tales of the Crusaders. […], volume II (The Betrothed), Edinburgh: […] [James Ballantyne and Co.] for Archibald Constable and Co.; London: Hurst, Robinson, and Co., page 187

A murrain on you, Reverend Apse/I hope you get caught in a vicious moral lapse.

1930, Ogden Nash, Lines to Be Mumbled at Ovington's

Usura is a murrain, usura blunteth the needle in the maid’s hand and stoppeth the spinner’s cunning.

1935, Ezra Pound, Canto XLV